Medisinen ble opprinnelig utviklet i Frankrike til bruk i det franske forsvaret. Den skulle brukes av det franske flyvåpenets soldater, slik at de skulle fileøle mindre tretthet og klare å konsentrere seg bedre om oppgavene sine.Della Marca et al (2004) researched sensory evoked potentials in human beings given modafinil and found that modafinil

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